careers@pes.edu +91-8055524555
Biotechnology
RingRoadCampus
shantikoppala@pes.edu
+91-80-26721983

Dr. Shanti K N

Professor, Chairperson
Bio
Teaching
Responsibilities
Research
Publications

Dr.K.N.Shanti has a Master degree In Biochemistry from Osmania University and Ph.D in Immunology from Indian Institute of Science, Bangalore. She has a very strong academic record being a distinction student throughout and a gold Medalist both in B.Sc and M.Sc. She was awarded a gold medal for the best Ph.D thesis at Indian Institute of Science .She was also conferred a Gold Medal and Young Scientist award at the National level By The Indian Immunology Society. Her Ph.D work on "Identification of Tropomyosin as the major shrimp allergen and characterization of its IgE binding epitopes" has been regarded as a land mark contribution which was cited both by National Media and also by New York Times, USA and National Institute of Health, Washington, USA. She is a Life Member of Academic Bodies like Indian Immunology Society, The Indian Science Congress, Society of Biological Chemists and Indian Society of Technical Education. She has vast teaching, research and administration experience of over two and a half decades. She has guided many graduate and post graduate students in the field of Engineering, Science and Pharmacy. Currently she is guiding 5 Ph.D and 2 M.Sc (engg) students. She has several International publications with high impact factor to her credit. Her areas of research Interest include Immunology, Phytochemistry, Biopharmaceuticals, Biofuels and Phytoremediation. Currently, She is a Professor and Chairperson at the Department of Biotechnology, PES University, Bangalore. She was appointed by the Central Government as Member of the University Grants Commission for a term of three years. She was also a Member of several prestigious committees: Member of the Governing Board of UGC-Department of Atomic Energy Consortium for Scientific Research, Indore. Member of the Advisory committee for Research Centre for Women's studies, Karnatak University , Dharwad. Member of the Advisory committee in Karnataka State Women's University,Vijayapur. She was also appointed as Court member of the Central University of Karnataka.

Education

  • M.Sc. Biochemistry, Osmania University 1985
  • Ph.D, Indian Institute of Science 1994

Experience

  • Professor, PES University, 2011-to date
  • Lecturer to Professor, Bharathi College, 1993-2011

Additional Information

  • Member of the University Grants Commission (2014-17)
  • Member of the Governing Board of UGC-Department of Atomic Energy Consortium for Scientific Research, Indore (2014-17)
  • Member of the Advisory committee for Research Centre for Women?s studies , Karnatak University , Dharwad, (2014-17)
  • Member of the Advisory committee in Karnataka State Women?s University ,Vijayapur (2014-17)
  • Court member of the Central University of Karnataka, (2014-17)
  • Member of the Governing Board of Inter University Centre for Astronomy and Astrophysics (IUCAA), (2015-18)

Achivements

  • Gold Medalist both in B.Sc and M.Sc.
  • Gold medal for the best Ph.D thesis at Indian Institute of Science
  • Gold Medal and Young Scientist award at the National level by The Indian Immunology Society.
  • Ph.D work on "Identification of Tropomyosin as the major shrimp allergen and characterization of its IgE binding epitopes" has been regarded as a land mark contribution which was cited both by National Media and also by New York Times, USA and National Institute of Health, Washington, USA.
  • PG courses: Pharmaceutical Biotechnology, Advanced Biochemistry, Clinical Biochemistry, Downstream Process technology, Pharmacognosy, Molecular Biology
  • UG Courses: Biochemistry : Biomolecules, Biochemistry : Metabolism, Immunology, Drug Development and Toxicology, Clinical trials, Research Methodology, Forensic Biology.
  • Chairperson, Department of Biotechnology.
  • Domain head, Medical and Environmental Biotechnology
  • Member ,University Grants Commission (2014-17)
  • Court member of the Central University of Karnataka, (2014-17)
  • Member of the Governing Board of Inter University Centre for Astronomy and Astrophysics (IUCAA), (2015-18)
  • Member of the Advisory committee for Research Centre for Women?s studies , Karnatak University , Dharwad, (2014-17)
  • Member of the Advisory committee in Karnataka State Women's University ,Vijayapur (2014-17)
  • Member of the Governing Board of UGC-Department of Atomic Energy Consortium for Scientific Research, Indore (2014-17)
  • Chief Superintendent for VTU examinations.

Research Interest

  • Immunology
  • Protein Chemistry
  • Pharmaceutical Biotechnology
  • Cancer and antidiabetic therapeutics

Research Projects (Current)

  • Identification, characterisation and validation of Pebrine targets: In-vitro and In-silico approach

Research Guidance

  • Research Supervisor for 5 Ph.D students
  • Research Supervisor for 2 Mtech by Research students
  • Two students have submitted their thesis

Conferences

  • Poster presentation titled "Antileukemic activity of Methanolic extracts of Plantago Ovata" at International Conference on "Next Generation Pharmacist In Pharmaceutical Industry & In Clinical Practice" on 17th and 18th October, 2015 at PES Institute of Technology, Bangalore
  • Poster presentation titled "Cytotoxic activity of leaf extract of Justicia wynaadensis on cancer cell lines" at International Conference on "Next Generation Pharmacist In Pharmaceutical Industry & In Clinical Practice" on 17th and 18th October, 2015 at PES Institute of Technology, Bangalore
  • Poster presentation titled "Evaluation of antitumour effect of Justicia wynaadensis an endemic plant at at National conference on "Trends in Pharmaceutical Biotechnology", conducted by Maharani Ammanni College for Women, Bengaluru, on 27th-28th Mar. 2015.
  • Oral paper presentation of paper entitled "Evaluation of anti oxidant and anti tumor activities of crude extracts of J. wynaadensis" at National level Biotechnology Symposium 2016 held at Manipal Institute of Technology in April 2016. Won Second prize
  • Oral paper presentation on "Evaluation of anti tumor activity of bioactive principle from J. Wynaadensis and analysis of in silico docking studies" at National level Biotechnology Symposium 2016 held at Manipal Institute of Technology in April 2016. Won First prize
  • Oral Paper Presentation on "Antileukemic activity of hexane purified fraction of methanolic root extract of Rubia cordifolia" at Asian Plant Science Conference' held at Hotel Nirvana, Paklihawa Road,Siddhartha Nagar (Bhairahawa), Lumbini, Nepal during November 1-3,2014.
  • Oral Presentation on "QCMB Biosensor for Rapid detection of agglutination reaction as a function of frequency change" at Symbiot 14 , the National Technical Symposium of I.E. Biotechnology, DRDO& The Dept of Biotechnology MIT, MANIPAL UNIVERSITY (11th & 12th April 2014)- Won the 2nd position in Paper presentation
  • Oral Presentation on "Study of the expression of PTEN and MTOR genes in glioma patients" at Symbiot 14 , the National Technical Symposium of I.E. Biotechnology, DRDO& The Dept of Biotechnology MIT, MANIPAL UNIVERSITY (11th & 12th April 2014)- Won the 3rd position in Paper presentation
  • Oral Presentation on "Evaluation of antioxidant properties of Cardiospermum halicacabum by in vitro assays" at Symbiot 14 , the National Technical Symposium of I.E. Biotechnology, DRDO& The Dept of Biotechnology MIT, MANIPAL UNIVERSITY (11th & 12th April 2014)
  • Oral Presentation on "Evaluation of antioxidant potential of Plantago ovata" (Isabgol seeds) at 8th Mile 2014 under Biotech Chemical Paper presentation conducted by The Dept of Biotechnology RVCE , Bangalore (19th to 23rd March 2014)
  • Oral Presentation on "Evaluation of antioxidant potential of Plantago ovata" at Symbiot 14 , the National Technical Symposium of I.E. Biotechnology, DRDO& The Dept of Biotechnology MIT, MANIPAL UNIVERSITY (11th & 12th April 2014) ? Won the 2nd position in Paper presentation.
  • Poster presentation on "Phytochelatins and their potential to sense Toxic trace metals" at the 5th Annual Meeting of Proteomics Society India, IISc ( Nov 28-30, 2013)
  • Oral Presentation on "Antitumour activity of Methanolic extracts of Rubia cordifolia root" at the National Conference on Emerging trends In Bioprocessing & Simulation organized at PES Institute of Technology (12th & 13th September 2013)
  • Oral Presentation on "Evaluation of antioxidant and antiproliferative property of Phytochemicals obtained from Vitex negundo leaves" at the National Conference on Recent advances in Nanoscience and Technology organized at Acharya Institute of Technology (3rd & 4th May2013)
  • Oral Presentation on "Antioxidant profiling and comparative analysis of "Durantha goldiana and Shilajit using invitro and platforms" at the National Conference on Recent advances in Nanoscience and Technology organized at Acharya Institute of Technology (3rd & 4th May2013)
  • Oral Presentation on "Isolation of Phytochelatins from Glycine max and Spinacia oleracea on exposure to heavy metals" at the National Conference on Recent advances in Nanoscience and Technology organized at Acharya Institute of Technology (3rd & 4th May2013)
  • Oral Presentation on "Development of an Optimised Microbial Fuel cell for Bioelectricity generation" at the National Conference on Recent advances in Nanoscience and Technology organized at Acharya Institute of Technology (3rd & 4th May2013)
  • Oral Presentation on "Invitro evaluation of antioxidant activities of Rubia cordifolia extracts" at the National Conference on Recent advances in Nanoscience and Technology organized at Acharya Institute of Technology (3rd & 4th May2013)
  • Poster Presentation on "Isolation of Phytochelatins and evaluation of its metal chelating capacity" at the National Seminar-cum-Workshop on "Sensor and Sensing system for Taste Characterisation of food and agroproducts" organized at IIT ,Kharagpur (9th & 10th May 2013)
  • Oral Presentation on "Receptor embedded in Liposomes as therapeutic agents" at the National Biotechnology Symposium organized at Manipal Institute of Technology (12th -14th April 2013)
  • Oral presentation On "Microbial cells" at the 2 day National Level Technical Symposium organized at Adhiyamaan College of Engineering and secured the First Prize (27th -28th Sep 2012).
  • Mutational studies of Serratia marcescens for the production of Serrapeptidase. Shanti.K.N., Gurukar Mathew.S., Tamizh Mani.T., Mohd.Shamseer., MBPP - 08 poster presentation in the National Conference on Medical Biotechnology & Clinical Research., 2009.
  • G. N. Shubha, K. N. Shanti, Rukmini Jonnalagadda, Richa Kamboj, Sucheta Sridhar, Antioxidant and Antileukemic Activity of Vitex negundo Leaf Extracts, International Journal of Pharmaceutical Sciences And Research, (2016); Vol. 7(12): 5056-5061.
  • Shanti.K.N, K.A Ganesh, D.Rajagopal, D.D.Metcalfe and P.V.Subba Rao, Two synthetic peptides derived from shrimp tropomyosin exhibit allergenicity. Allergologie, Suppl No. 2 : 316 (1994).
  • Shanti. K.N., B.M.Martin., D.D.Metcalfe and P.V.Subba Rao, Identification of Tropomyosin as the major shrimp allergen and characterization of its IgE binding epitopes. Proc XIX Annual Conference of Indian Immunol.Soc. 16 (1993).
  • Shanti.K.N., S.Nagpal, D.D.Metcalfe and P.V.Subba Rao, Cross-reactivity of shrimp, prawn and lobster allergens New England and Regional Allergy proc., 9:408 (1988).

Journals

  • C.D. Vandana, K.N. Shanti, Prashantha Karunakar, Vivek Chandramohan, In silico studies of bioactive phytocompounds with anticancer activity from in vivo and in vitro extracts of Justicia wynaadensis (Nees) T. Anderson, Int. J. Computational Biology and Drug Design, Vol. 13, Nos. 5/6, 2020 https://dx.doi.org/10.1504/IJCBDD.2020.113836
  • Jyosthna S, Navyashree, TG, Dinesh.M.S. Shanti.K.N. and Kavitha.S.H. 2020, Development of organic millet malt formulation for enhanced nutraceutical value, International conference on emerging trends in food protectants and infestation control, organised by CFTRI, 24-25 Dec.,2020
  • Chandana, M, Samyuktha,S Dinesh M S and Shanti.K.N.Peptide antibiotics from Sericin nanoparticles,2020, International Journal of Nanomedicine, Vol.16 (3),19-23.
  • Raveen Armstrong, Vinod kumar, Versha Kamath, Dinesh.M.S. and Shanti.K.N 2020, Vermiwash as biofungicide to control plant pathogen , International Journal of plant
  • Meghna.N. Dhruv Kapila, Aryamitra, Dinesh.M.S. Shanti.K.N.2020 Scope and Significance of Nanobifertilizers, Journal of Nanotrends,Vol.20(6), 33-45
  • Komadi.S. maharani, Dinesh.M.S. Shanti K N and Kavitha.S.H.2020., Development of Organic disinfectant from Indigenous aromatic plants,International Journal of Scientific and Engineering Research, Vol.4(2),9-18.
  • Dinesh.M.S. Ravindra.M. V.Krishnamurthy, Shanti.K.N. and Kavitha.S.H Application of vermiwash as plant hormone in micropropogation of Stevia raubidiana,Asia-Pacific Journal of Chemical Engineering., 2019Vol.14(B).(6).,pp.,1-10. ISSN:1932 2135
  • Dinesh.M.S. Suhas. S. Praveen. Chandrakanth, Krishnamurthy,V and Shanthi.K.N. Probiotic vermiwash to enhance the Cocoon weight and yield in Bombyx mori, Sericologia, International Journal of Sericulture (2019), 16(1), 55-70
  • Ashrith Mangal Wedhekar, Malvika Ramani, Archana Gopalakrishnan, M.S.Dinesh, Geetha.K.S. K.N.Shanti and V.Krishnamurthy, Green Synthesis of Pectin nanoparticles for Novel Nutraceutical Development, International Journal of Scientific Research (2018). Vol.9(5).,1-7
  • M.Shreyas., Mithun Raj. U.,Sharath, Dinesh.M.S. V.Krishnamurthy and Shanti.K.N, Synthesis of Silver Nanoparticles from Phytoextracts and Testing their potential Anticancerous Activity, Nanotrends: Journal of Nanotechnology and applications (2018), Vol.20(S),1, 1-10
  • C.D.Vandana, K.N.Shanti and S.L. Shantha, GC-MS analysis of callus and leaf extracts of in vitro propagated plants of Justicia Wynaadensis (Nees) T.Anderson, International Journal of Pharmaceutical Sciences and Research, Feb (2018), Vol.9 (2) 535-43
  • C.D. Vandana & K.N.Shanti, Cytotoxic activity of Justicia Wynaadensis (Nees) T.Anderson Leaf extract on Human Cancer Cell lines, International Journal of Pharmaceutical sciences and Research (2017) 8(12). 5298 -5302
  • Shanti Koppala N, Shubha Gattadahalli Nanjundaswamy, Aanchal Preet Kaur, Gargi Nandkishor Deshmukh, Shravya Vasanth and Ananda S , Antioxidant & anti-leukemia activity of Methanolic extracts of Plantago ovata . International Journal of Pharmaceutical Research & Development, (2016) Vol 8 (1), 001-009
  • PRIYANKA, R, VASUNDHARA,M., ASHWINI JAYARAM, RAO, G.G.E, NARAPPA, N. AND SHANTHI, K.N., 2015, "Effect of Processing on volatile oil composition in Turmeric (Curcuma longa L) varieties", The Ecoscan: 9(3&4): 683-687. NAAS: 5.06.
  • Priyanka R. Vasundhara, M., ASHWINI JAYARAM, RADHIKA, B., AND SHANTI K.N. 2014, "Screening Fresh, dry and processed Turmeric (Curcuma longa L) Extract Against Pathogenic Bacteria. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 5(6): 1041 -1046.
  • Shanti. K.N., B.M.Martin., S.Nagpal., D.D.Metcalfe and P.V.Subba Rao, Identification of Tropomyosin as the major shrimp allergen and characterization of its IgE binding epitopes. J.Immunol., 151: 5354-5363 (1993).
  • Nagpal.S., K.N.Shanti, R.Kori, H.Schroder, D.D.Metcalfe and P.V.Subba Rao, Induction of allergen specific IgE and IgG responses by anti-idiotypic antibodies.. J.Immunol., 142:3411-3415 (1989).
  • Shanti.K.N, B.Martin, G.Venkataraman, S.Nagpal and D.D.Metcalfe, Tropomyosin is the major shrimp allergen. Subba raoPV., J.Allergy.Clin.Immunol. 91(Part II): 341 (1993).